Curamin
~ Stop Pain Now ~
A unique combination, this fast-acting formula combines ingredients with multiple mechanisms of action to support the body’s natural anti-inflammatory response and relieve occasional muscle pain due to exercise and overuse.
Ingredients:
DLPA (DL-phenylalanine) - is an amino acid consisting of equal parts D-phenylalanine and L-phenylalanine. D-phenylalanine inhibits the breakdown of compounds called enkephalins. Enkephalins are associated with positive mood and have been shown to relieve occasional muscle pain due to exercise or overuse.* L-phenylalanine is converted into tyrosine, which in turn is used to produce the brain chemicals norepinephrine and dopamine.1-3
Boswellia (Boswellia serrata) - Clinically tested boswellia (BosPure) helps reduce the activity of the inflammatory enzyme, 5-LOX (lipoxygenase).* A compound (beta boswellic acid) found in boswellia which interferes with its beneficial activity has been removed, greatly increasing the effectiveness of this extract.4,5
Curcumin (Curcumin longa) - Curcumin, a compound found in the spice turmeric, inhibits multiple inflammation pathways in the body. It is also a potent antioxidant. Some of the benefits associated with curcumin include immune system modulation, protection from oxidative stress, and support for the body’s natural anti-inflammatory response.* The specialized extract in this formula has the highest absorption of any curcumin extract available for maximum health benefits.6-12
Nattokinase - The enzyme nattokinase helps promote blood flow, aiding the other ingredients in the formula to reach all areas of the body.*12,13
Significant clinical results in published human studies.
- Ehrenpreis S. Analgesic properties of enkephalinase inhibitors: animal and human studies. Prog Clin Biol Res. 1985;192:363-70.
- Ehrenpreis S. D-phenylalanine and other enkephalinase inhibitors as pharmacological agents: implications for some important therapeutic application. Acupunct Electrother Res. 1982; 7(2-3):157-72.
- DLPA. In: Hendler SS, ed. PDR for Nutritional Supplements. 2nd ed. Montvale, NJ: Physician’s Desk Reference; 2008:189.
- Ammon HP. Boswellic acids in chronic inflammatory diseases. Planta Med. 2006 Oct; 72(12):1100-16.
- Poeckel D, Tausch L, Altmann A, et al. Induction of central signalling pathways and select functional effects in human platelets by beta-boswellic acid. Br J Pharmacol. 2005 Oct; 146(4):514-24.
- Jurenka JS. Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research. Altern Med Rev. 2009 Jun; 14(2):141-53.
- Jacob A, Wu R, Zhou M, Wang P. Mechanism of the Anti-inflammatory Effect of Curcumin: PPAR-gamma Activation. PPAR Res. 2007;89369.
- Johnson SM, Gulhati P, Arrieta I, et al. Curcumin inhibits proliferation of colorectal carcinoma by modulating Akt/mTOR signaling. Anticancer Res. 2009;29(8):3185-90.
- Ravindran J, Prasad S, Aggarwal BB. Curcumin and cancer cells: how many ways can curry kill tumor cells selectively? AAPS J. 2009; 11(3):495-510.
- Seehofer D, Schirmeier A, Bengmark S, et al. Curcumin Attenuates Oxidative Stress and Inflammatory Response in the Early Phase after Partial Hepatectomy with Simultaneous Intraabdominal Infection in Rats. J Surg Res. 2008 Dec 31.
- Biswas S, Rahman I. Modulation of steroid activity in chronic inflammation: a novel anti-inflammatory role for curcumin. Mol Nutr Food Res. 2008; 52(9):987-94.
- Benny B, Antony B. Bioavailability of Biocurcumax (BCM-95). Spice India. September, 2006:11-15.
- Hsia CH, Shen MC, Lin JS, et al. Nattokinase decreases plasma levels of fibrinogen, factor VII, and factor VIII in human subjects. Nutr Res. 2009; 29(3):190-6.
- Fujita M, Hong K, Ito Y, Fujii R, Kariya K, Nishimuro S. Thrombolytic effect of nattokinase on a chemically induced thrombosis model in rat. Biol Pharm Bull. 1995; 18(10):1387-91.
